Brighton go into the game in 14th place, with the 'Swans' only a point below in 16th. The 'Seagulls' are unbeaten in three games while the Welsh side have seen a huge upturn in fortunes since appointing Carlos Carvahal as manager.
"We are playing a team in very good form at the moment and where we are in the division, these are certainly the games you don't want to lose," said Hughton.
"It's certainly a massive game, until the next massive game, that's how it is at the moment.
"We are in good form though and will need to use that good form and home advantage to give ourselves the best possible chance of getting the result. At this stage of the season, these games become more meaningful."
Hughton was also full of praise for the work that Carvahal has done at Swansea and the attitude he has instilled at the club: "It has stemmed from a change of manager but if you spoke to him, he would talk about what the players have given him.
"He is a very good manager, we know him well from our exploits in the Championship. He is a very experienced manager and at the moment he is getting the best out of them."
Brighton - Swansea kicks off at 3pm GMT on Saturday.